Detalhe da pesquisa
1.
Clonal selection of stable aneuploidies in progenitor cells drives high-prevalence tumorigenesis.
Genes Dev;
35(15-16): 1079-1092, 2021 08 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-34266888
2.
Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan.
Nature;
530(7589): 184-9, 2016 Feb 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-26840489
3.
The genetic background significantly impacts the severity of kidney cystic disease in the Pkd1RC/RC mouse model of autosomal dominant polycystic kidney disease.
Kidney Int;
99(6): 1392-1407, 2021 06.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33705824
4.
Autophagy activators suppress cystogenesis in an autosomal dominant polycystic kidney disease model.
Hum Mol Genet;
26(1): 158-172, 2017 01 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28007903
5.
Spartan deficiency causes accumulation of Topoisomerase 1 cleavage complexes and tumorigenesis.
Nucleic Acids Res;
45(8): 4564-4576, 2017 05 05.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28199696
6.
Experimental Models of Polycystic Kidney Disease: Applications and Therapeutic Testing.
Kidney360;
4(8): 1155-1173, 2023 08 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-37418622
7.
Genetic Spectrum of Polycystic Kidney and Liver Diseases and the Resulting Phenotypes.
Adv Kidney Dis Health;
30(5): 397-406, 2023 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-38097330
8.
BubR1 allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome.
J Clin Invest;
130(1): 171-188, 2020 01 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-31738183
9.
Two-Step Senescence-Focused Cancer Therapies.
Trends Cell Biol;
28(9): 723-737, 2018 09.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29776716
10.
Mosaic-variegated aneuploidy syndrome mutation or haploinsufficiency in Cep57 impairs tumor suppression.
J Clin Invest;
128(8): 3517-3534, 2018 08 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-30035751
11.
Cellular senescence in renal ageing and disease.
Nat Rev Nephrol;
13(2): 77-89, 2017 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-28029153
12.
BubR1 allelic effects drive phenotypic heterogeneity in mosaic-variegated aneuploidy progeria syndrome.
J Clin Invest;
130(11): 6188, 2020 11 02.
Artigo
em Inglês
| MEDLINE
| ID: mdl-33136097